Hyperlipidemia Is an Important Problem in Pediatric Renal Transplant Recipients

Background: Hyperlipidemia is common after solid organ transplantation and a risk factor for atherosclerosis. The aim of the present study was to detect prevalence of dyslipidemia and reveal lipid profile in pediatric renal transplantation. Material and Methods: This study was performed in children renal transplant recipients between the ages of 1 year to 18 years at Ege University. The follow-up time was at least 1 year after renal transplantation. After a 12-hour overnight fasting serum lipid profile were studied. Results: There were 53 (50.5%) male patients and 52 (49.5%) female patients. Fifty-six (53.3%) patients received a cadaveric kidney and 49 (46.7%) patients received living related kidney. The prevalence high total cholesterol level at 1, 2 and 5 years were found 39.4%, 33.2%, and and 36.4% respectively. The prevalence high LDL level at 1, 2 and 5 years were determined 39.1 %, 35.2 % and 36.2%, and 30.4%, respectively. But it was not statistically significant. The comparison of pretransplantation, first, second and fifth year’s group’s triglyceride levels for the presence of chronic allograft nephropathy (CAN) revealed no statistically significant difference. Conclusion: In conclusion, prevalence of hyperlipidemia is significantly high in pediatric renal transplant recipients. Lipid levels should be closely followed-up after renal transplantation.